Evaluation of Acute, Sub-Chronic Oral Toxicity Studies and Anti-Inflammatory Activity of Blumea mollis in Experimental Animals

Objective: The goal of this study was to test the ethanol extract aerial part Blumea mollis (Asteraceae) for acute and sub-chronic toxicity as well anti-inflammatory efficacy.
 Methods: shade dried (0.5 kg) powdered extracted with ethanol. Ethanol extracts used these studies. Acute oral studies were performed per OECD guidelines. effect studied by carrageenan-induced paw edema model in rats at dose levels 100, 200, 400 mg/kg, orally.
 Results: results indicate that found be safe 2000mg/kg. EBM 200 mg/kg exhibited significant inhibition (p<0.001) increase rats.
 Conclusion: experimental confirmed is devoid possesses activity.